Mouse Nucleolin / NCL Protein, Mouse IgG2a Fc Tag

• Background:

  Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

• Description:

  Mouse Nucleolin, Mouse IgG2a Fc Tag (NUL-M5253) is expressed from human 293 cells (HEK293) . It contains AA Val 2 - Glu 707 (Accession # P09405-1) .

• Specifications:

  This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 103.5 kDa. The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  P09405-1

• Expression Region:

  Val 2 - Glu 707

• Host:

  HEK293

• Target:

  Nucleolin

• Conjugation:

  Unconjugated

• Tag:

  C-mFc (mIgG2a)

• Source:

  Mouse

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  0.1 EU per μg

• Purity:

  90%

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  103.5 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  100ug*1

• Species:

  Mouse