Mouse IL-7 R alpha / CD127 Protein, Fc Tag

• Background:

  Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP) . The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

• Description:

  Mouse IL-7 R alpha Protein, Fc Tag (ILR-M5253) is expressed from human 293 cells (HEK293) . It contains AA Glu 21 - Asp 239 (Accession # Q9R0C1) .

• Specifications:

  This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.4 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  Q9R0C1

• Expression Region:

  Glu 21 - Asp 239

• Host:

  HEK293

• Target:

  IL-7 R alpha

• Conjugation:

  Unconjugated

• Tag:

  C-Fc

• Source:

  Mouse

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  0.1 EU per μg

• Purity:

  90%

• Bioactivity:

  Immobilized Mouse IL-7 R alpha Protein, Fc Tag (Cat. No. ILR-M5253) at 5 μg/mL (100 μL/well) can bind Mouse IL-7, His Tag (Cat. No. IL7-M52H3) with a linear range of 1-39 ng/mL (QC tested).

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  51.4 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  100ug*1

• Species:

  Mouse