Sildenafil-d3-1

• CAS Number:

  1126745-87-6

• UNSPSC Description:

  Sildenafil-d3-1 (UK-92480-d3-1) is deuterium labeled Sildenafil-d3. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM.

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1CCN(S(C2=C([2H])C([2H])=C(OCC)C(C3=NC(C(CCC)=NN4C)=C4C(N3)=O)=C2[2H])(=O)=O)CC1

• Molecular Weight:

  477.59

• References & Citations:

  [1]Wang Z, et al. The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA. J Sex Med. 2013 Nov;10(11):2790-7

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported