Androgen receptor degrader-5

• CAS Number:

  2902679-11-0

• UNSPSC Description:

  Androgen receptor degrader-5 (compound 14k) exhibits promising properties, including superior androgen receptor degradation activity and antiproliferative activity[1].

• Target Antigen:

  Androgen Receptor

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/androgen-receptor-degrader-5.html

• Smiles:

  O=C([C@@](C)(O)CN1CCN(C2=CC=C(C3=CC(F)=C(C#N)C=C3)C=C2)CC1)NC4=CC=C(C#N)C(C(F)(F)F)=C4

• Molecular Weight:

  551.53

• References & Citations:

  [1]Wenqiang Zhang, et al. Discovery of novel biphenyl derivatives as androgen receptor degraders for the treatment of enzalutamide-resistant prostate cancer. Bioorg Chem. 2024 Jul:148:107433.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported