N-Desmethyl clomipramine (hydrochloride)

• Product Name Alternative:

  Desmethylclomipramine (hydrochloride); Norclomipramine (hydrochloride)

• UNSPSC Description:

  N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant[1][2].

• Target Antigen:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/n-desmethyl-clomipramine-hydrochloride.html

• Purity:

  99.73

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  CNCCCN1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31.[H]Cl

• Molecular Weight:

  337.29

• References & Citations:

  [1]Sioufi A, et al. Simultaneous determination of clomipramine and its N-desmethyl metabolite in human whole blood by capillary gas chromatography with mass-selective detection. J Chromatogr. 1988 Jun 24;428(1):71-80.|[2]Härtter S, et al. Non-competitive inhibition of clomipramine N-demethylation by fluvoxamine. Psychopharmacology (Berl). 1995 Jan;117(2):149-53.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  29854-14-6