HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (MALS verified)

• Background:

  Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein C (gC) is a structural component of the herpes simplex virus type 2 (HSV-2) envelope that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Also plays a role in host immune evasion by inhibiting the host complement cascade activation (By similarity) .

• Description:

  HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (GLC-V52H3) is expressed from human 293 cells (HEK293) . It contains AA Leu 102 - Glu 446 (Accession # P06475) .

• Specifications:

  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.8 kDa. The protein migrates as 52-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  P06475

• Expression Region:

  Leu 102 - Glu 446

• Host:

  HEK293

• Target:

  Glycoprotein C/gC (HSV)

• Conjugation:

  Unconjugated

• Tag:

  C-10xHis

• Source:

  HSV-2

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  90%

• Bioactivity:

  Immobilized HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (Cat. No. GLC-V52H3) at 5 μg/mL (100 μL/well) can bind Anti-HSV2 gC antibody with a linear range of 0.6-78 ng/mL (QC tested).

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  39.8 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  100ug*1

• Species:

  HSV-2