Recombinant Human TPK1 Protein (His Tag)

• Background:

  Thiamin pyrophosphokinase 1 (TPK1), belongs to the thiamine pyrophosphokinase family. TPK1 exists as a homodimer, and is detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. TPK1 can catalyze the phosphorylation of thiamine to thiamine pyrophosphate. It can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.

• Abbreviation:

  TPK1

• Synonyms:

  PP20; Placental protein 20; TPK1; Thiamin pyrophosphokinase 1; Thiamine pyrophosphokinase 1; hTPK1

• UniProt:

  Q9H3S4

• Accession Number:

  AAH68460.1

• Expression System:

  HEK293 Cells

• Tag:

  C-His

• Sequence:

  Met 1-Ser243

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Not Applicable

• Shipping Conditions:

  This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

• Storage Conditions:

  Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

• Calculated Molecular Weight:

  28.3 kDa

• Observed Molecular Weight:

  30 KDa

• Formulation:

  Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

• Species:

  Human