Recombinant Human PDZD11/PDZK11/PISP Protein (His Tag)

• Background:

  PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein which contains onePDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11.

• Synonyms:

  AIPP1; PDZK11; PISP

• UniProt:

  Q5EBL8

• Accession Number:

  NP_057568.1

• Expression System:

  E. coli

• Tag:

  N-His

• Sequence:

  Asp 2-His 140

• Field of Research:

  Cell biology

• Endotoxin:

  Please contact us for more information.

• Purity:

  > 97 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  16.9 kDa

• Observed Molecular Weight:

  18 kDa

• Formulation:

  Lyophilized from sterile PBS, pH 8.0
  Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
  Please refer to the specific buffer information in the printed manual.

• Species:

  Human