Catalog Number: 24347 Price: 299 Euro
Lot Number: R5611
Quantity: 100 mg in 100 ml (1 mg/ml) in PBS containing 0.02% sodium azide.
Description: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
Host Species: Rabbit
Specificity: Reacts with residues 268-284 (SEAQPGQKHGQEEAAQS) of the human FBG2 protein.
Applications: Western blot – Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Format: Affinity purified IgG
Storage: Maintain at +2-8°C for 3 months or at -20°C for longer periods. Stable for 1 year. Avoid repeated freeze-thaw cycles.
Reference: Ilyin,G.P. et al. Gene. 2002 Aug 21;296(1-2):11-20.