GENTAUR Contact Gentaur

Up

GENTAUR Survey

GENTAUR EUROPE

+32 1658 9045
+32 1650 9045

BELGIUM1

tel +32 2 732 5688
fax +32 2 732 4414
info@gentaur.com
Av. de l' Armée 68
B-1040 Brussels

France

tel 01 43 25 01 50
fax 01 43 25 01 60
9, rue Lagrange
75005 Paris

Italy

tel 02 36 00 65 93
fax 02 36 00 65 94
20135 Milano

Germany

tel +32 16 58 90 45
fax +32 16 50 90 45
Forckenbeckstraße 6
D-52074 Aachen

Japan

tel +81 78 386 0860
fax +81 78 306 0296
Minaatojimaminami-manchi
Chuo-ku, Kobe
065-0047


Filgrastim (rHuG-CSF)

 

 

l        Description

Filgrastim is a human granulocyte colony stimulating factor (G-CSF), produced by recombinant DNA technology by E.coli. It is 175 amino acid protein, non-glycosylated, and has a molecular weight of approximately 18.8kD. The protein has an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine necessary for expression in E. coli.

 

l        Indication

1.        Neutropenia resulting from cancer chemotherapy.

2.        Neutrophil decrease after bone marrow transplantation.

3.        Neutropenia caused by Myelodysplastic syndrome, neutropenia caused by aplastic anemia; congenital neutropenia, idiopathic neutropenia, Myelodysplastic syndrome with neutropenia and Periodic neutropenia.

4.        Patients undergoing peripheral blood progenitor cell collection and therapy.

 

l        Pharmaceutical particulars

Sterile, clear, colorless and preservative-free liquid for injection in vial

Dosage: 75μg/vial, 150μg/vial, 300μg/vial and 480μg/vial

Reference: Chinese Pharmacopoeia

Specific activity: ≥0.8×108IU/mg
Purity
(HPLC, SDS-PAGE): ≥98%

 

l        Composition

 Active ingredients: Filgrastim (rHuG-CSF).

 Inactive ingredients: Glacial Acetic Acid, Mannitol, Polysorbate 80 and Sodium Acetate.

 

l        Shelf life and storage conditions

 Finished formulation  Store at 2-8 for 2 years
 API (Concentrated solution)  Store at 2-8 for 7 months
 

Home Up

send mail to webmaster@gentaur.com with questions or comments about this web site.
Copyright © 2008 Gentaur Molecular Products
Site powered by Acid Dragon (AC)
Last modified: 05/19/16