Would you like to simplify and standardize your cell invasion and migration assays?

Cultrex^® Cell Invasion Assays accelerate the screening process for compounds that influence cell migration through extracellular matrices. These assays offer a flexible, standardized, in vitro, high throughput format for quantitating the degree to which invasive cells penetrate a barrier consisting of basement membrane components in response to chemoattractants and/or inhibiting compounds.

The Cultrex^® Cell Invasion Assays are available in 24 or 96 well options and have been adapted to multiple formats so that cell invasion may be evaluated against different extracellular matrices: Basement Membrane Extract (BME), Laminin I, Collagen I, and Collagen IV. The assay has been functionally tested with MCF7, HT1080, NIH3T3, and MDA-MB-231 cell lines. Each lot of kits has been tested to ensure that the invasive cell line HT-1080, penetrates a barrier consisting of an 8 micron polyester membrane coated with basement membrane components while the non-invasive cell line MCF7, does not penetrate this barrier. 

Studying cell migration without using matrices?  The Cultrex^® Cell Migration Assay kit is an alternative to the invasion kits providing a screening process for compounds that influence chemotaxis rather than invasion.  The kit includes fluorescent staining reagents, buffers, cell dissociation solution and is available in a 24 or 96 well format.

Did you know that you can measure angiogenesis directly? Trevigen has a complete line of in vivo and in vitro assays for the direct measurement of angiogenesis. Please follow the links below for more information.

Trevigen also offers a complete line of Basement Membrane Extract products and specialty proteins to compliment our angiogenesis product portfolio, including bovine collagen I, rat collagen I, mouse collagen IV, mouse laminin I, bovine fibronectin, and bovine vitronectin.

Trevigen products include over 500 kits and reagents in the areas of DNA damage, apoptosis and cell behavior. I invite you to visit our website at www.trevigen.com for additional product information or contact your local distributor.